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Investing in Medical Technology

Understanding Medical Technology:

Exploring New Frontiers with Maybank Strategic Growth-I Fund

Medical Technology: Pulsed Field Ablation

Sources: CDC

Atrial fibrillation (“AFib”): A Silent Killer


32%

of global deaths are caused by cardiovascular disease.


85%

of these deaths were due to heart attack and stroke, and AFib increases the risk of stroke.


What is AFib?

AFib is an irregular heart rhythm that may lead to compilation like heart failure.

Sources: JNJ Medtech

Sources: JNJ Medtech

In 2021,

43 million

people suffered Afib globally


It is expected to reach

72 million

Afib patients by 2050, placing huge burden across the globe

Pulsed Field Ablation (“PFA”): Revolutionizing AFib Treatment

  • PFA is a technique used to treat arrhythmias like AFib by delivering electrical pulses to disrupt abnormal heart tissue.
  • Medical technology companies are enhancing AFib treatment by replacing traditional methods with PFA.
  • PFA reduces the risk and delivers high efficacy, shorter procedure times, and superior safety profile with lower complication rate.
Feature Pulsed Field Ablation (PFA) Cryoballoon Ablation (CRYO) Radiofrequency Ablation (RF)
First-Pass Isolation Rate 98.8% 98.8% 73.1%
Procedure Time Shorter (average 94 minutes) Longer (average 76 minutes) Longer (average 157 minutes)
Complication Rates ~3.4% ~8.6% ~5.5%
Phrenic Nerve Palsy Risk None Reported Risk present Risk present
Long-Term Freedom from AFib 79.3% at 1 year 74.7% at 1 year 72.4% at 1 year

Source: National Library of Medicine, Cardiovascular Research Foundation, Journal of the American College of Cardiology

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